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Other factors include: Underlying cause of deficiency : Pernicious anaemia, malabsorption disorders, or dietary insufficiency may affect treatment response Medication use : Metformin and proton pump inhibitors can reduce gastrointestinal B12 absorption (though this does not affect the efficacy of intramuscular injections) Individual variation : Differences in how efficiently your body utilises the injected vitamin Adherence to treatment schedule : Missing injections or delaying maintenance doses can slow recovery Discussing these factors with your healthcare provider helps set realistic expectations for your treatment journey

However, there are certain health conditions and circumstances that may be negatively affected by the injections, including: Pregnancy Breastfeeding Cancer Advanced liver disease Seriously compromised kidney function Hypotension 4 Your Provider Injects Vitamin B12 Shots Intramuscularly This means the solution gets injected directly into your muscles

While B12 is naturally found in foods like meat, eggs, and dairy, some individuals have difficulty absorbing enough through diet alone

Lifestyle factors greatly influence ones Vitamin B levels